EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.15.15 | 1alpha-hydroxyvitamin D3 | competes with 5beta-cholestane-3alpha,7alpha,12alpha-triol | Rattus norvegicus | |
1.14.15.15 | 5beta-cholestane-3alpha,7alpha,12alpha-triol | competes with 1alpha-hydroxyvitamin D3 | Rattus norvegicus | |
1.14.15.15 | N-bromosuccinimide | 50% loss of activity at 0.1 mM | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.15.15 | mitochondrion | - |
Rattus norvegicus | 5739 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.15.15 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.14.15.15 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.15.15 | liver | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.14.15.15 | 0.00233 | - |
1alpha-hydroxyvitamin D3 as substrate | Rattus norvegicus |
1.14.15.15 | 0.114 | - |
5beta-cholestane-3alpha,7alpha,12alpha-triol as substrate | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.15.15 | 1alpha-hydroxyvitamin D3 + reduced adrenodoxin + O2 | 25-hydroxylation | Rattus norvegicus | 1alpha,25-dihydroxyvitamin D3 + oxidized adrenodoxin + H2O | - |
? | |
1.14.15.15 | 5beta-cholestane-3alpha,7alpha,12alpha-triol + reduced adrenodoxin + O2 | - |
Rattus norvegicus | 5beta-cholestane-3alpha,7alpha,12alpha,27-tetrol + oxidized adrenodoxin + H2O | - |
? | |
1.14.15.15 | 5beta-cholestane-3alpha,7alpha-diol + reduced adrenodoxin + O2 | - |
Rattus norvegicus | ? | - |
? |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.14.15.15 | 45 | - |
90% loss of activity after 2 min | Rattus norvegicus |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.15.15 | 0.0233 | - |
1alpha-hydroxyvitamin D3 | - |
Rattus norvegicus | |
1.14.15.15 | 0.217 | - |
5beta-cholestane-3alpha,7alpha-diol | - |
Rattus norvegicus | |
1.14.15.15 | 0.6 | - |
5beta-cholestane-3alpha,7alpha,12alpha-triol | - |
Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.15.15 | 0.004 | - |
5beta-cholestane-3alpha,7alpha,12alpha-triol | - |
Rattus norvegicus |