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Literature summary extracted from

  • Martinez, A.; Andersson, K.K.; Haavik, J.; Flatmark, T.
    EPR and 1H-NMR spectroscopic studies on the paramagnetic iron at the active site of phenylalanine hydroxylase and its interaction with substrates and inhibitors (1991), Eur. J. Biochem., 198, 675-682.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.16.1 dithiothreitol
-
 Bos taurus
1.14.16.1 dithiothreitol
-
 Rattus norvegicus
1.14.16.1 Tris
-
 Bos taurus
1.14.16.1 Tris
-
 Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.16.1 Iron one-dimensional 1H-NMR spectroscopy of iron Rattus norvegicus
1.14.16.1 Iron one-dimensional 1H-NMR spectroscopy of iron Bos taurus
1.14.16.1 Iron iron-protein Rattus norvegicus
1.14.16.1 Iron iron-protein Bos taurus
1.14.16.1 Iron electron paramagnetic resonance spectrum Rattus norvegicus
1.14.16.1 Iron electron paramagnetic resonance spectrum Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.14.16.1 Bos taurus
-
-
-
1.14.16.1 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.16.1
-
 Rattus norvegicus
1.14.16.1
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.16.1 liver
-
 Rattus norvegicus
-
1.14.16.1 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.16.1 L-phenylalanine + tetrahydrobiopterin + O2
-
 Rattus norvegicus L-tyrosine + dihydrobiopterin + H2O
-
 ?
1.14.16.1 L-phenylalanine + tetrahydrobiopterin + O2
-
 Bos taurus L-tyrosine + dihydrobiopterin + H2O
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.16.1 tetrahydrobiopterin
-
 Rattus norvegicus
1.14.16.1 tetrahydrobiopterin
-
 Bos taurus