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Literature summary extracted from

  • Wojtczak, A.B.; Walajtys, E.
    Mitochondrial oxaloacetate decarboxylase from rat liver (1974), Biochim. Biophys. Acta, 347, 168-182.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.112 p-chloromercuribenzoate
-
 Cavia aperea
4.1.1.112 p-chloromercuribenzoate
-
 Oryctolagus cuniculus
4.1.1.112 p-chloromercuribenzoate 50% inhibition at 0.5 mM Rattus norvegicus
4.1.1.112 Zn2+ 54% inhibition at 1.5 mM Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.112 0.55
-
 oxaloacetate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.112 cytoplasm
-
 Rattus norvegicus 5737
-
4.1.1.112 cytoplasm
-
 Oryctolagus cuniculus 5737
-
4.1.1.112 cytoplasm
-
 Cavia aperea 5737
-
4.1.1.112 mitochondrion
-
 Rattus norvegicus 5739
-
4.1.1.112 mitochondrion
-
 Oryctolagus cuniculus 5739
-
4.1.1.112 mitochondrion
-
 Cavia aperea 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.112 oxaloacetate Rattus norvegicus
-
 ?
-
 ?
4.1.1.112 oxaloacetate Oryctolagus cuniculus
-
 ?
-
 ?
4.1.1.112 oxaloacetate Cavia aperea
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.112 Cavia aperea
-
 guinea pig
-
4.1.1.112 Oryctolagus cuniculus
-
 rabbit
-
4.1.1.112 Rattus norvegicus
-
 rat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.112 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.112 brain
-
 Rattus norvegicus
-
4.1.1.112 kidney
-
 Rattus norvegicus
-
4.1.1.112 liver
-
 Rattus norvegicus
-
4.1.1.112 liver
-
 Oryctolagus cuniculus
-
4.1.1.112 liver
-
 Cavia aperea
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.112 additional information
-
-
 Rattus norvegicus
4.1.1.112 additional information
-
-
 Oryctolagus cuniculus
4.1.1.112 additional information
-
-
 Cavia aperea

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.112 Oxaloacetate
-
 Oryctolagus cuniculus Pyruvate + CO2
-
 ?
4.1.1.112 Oxaloacetate
-
 Cavia aperea Pyruvate + CO2
-
 ?
4.1.1.112 Oxaloacetate reaction mechanism Rattus norvegicus Pyruvate + CO2
-
 ?
4.1.1.112 oxaloacetate
-
 Rattus norvegicus ?
-
 ?
4.1.1.112 oxaloacetate
-
 Oryctolagus cuniculus ?
-
 ?
4.1.1.112 oxaloacetate
-
 Cavia aperea ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.112 30
-
 enzyme assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.112 6.5 7.5
-
 Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.1.1.112 0.5
-
 p-chloromercuribenzoate
-
 Rattus norvegicus