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Literature summary extracted from

  • Ng, S.K.; Wong, M.; Hamilton, I.R.
    Properties of oxaloacetate decarboxylase from veillonella parvula (1982), J. Bacteriol., 150, 1252-1258.
    View publication on PubMedView publication on EuropePMC

General Stability

EC Number General Stability Organism
4.1.1.112 buffer-dependent, mercaptoethanol stabilises Veillonella parvula

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.112 ATP carboxylation competitively inhibited, decarboxylation non-competitively, Ki: 2.2 mM, possibly involved in regulation Veillonella parvula

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.112 0.06
-
 oxaloacetate
-
 Veillonella parvula
4.1.1.112 1
-
 CO2
-
 Veillonella parvula
4.1.1.112 3.3
-
 pyruvate
-
 Veillonella parvula

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.1.112 Mg2+ required, decarboxylation Km: 0.17 mM, carboxylation Km: 1.85 mM Veillonella parvula
4.1.1.112 Mn2+ required Veillonella parvula

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.112 oxaloacetate Veillonella parvula
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.112 Veillonella parvula
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.112
-
 Veillonella parvula

Reaction

EC Number Reaction Comment Organism Reaction ID
4.1.1.112 oxaloacetate = pyruvate + CO2 Keq: 0.00213 1/mM, decarboxylation favored Veillonella parvula
a
4.1.1.112 oxaloacetate = pyruvate + CO2 pyruvate + CO2 = oxaloacetae Veillonella parvula
a

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.112 18.9
-
-
 Veillonella parvula

Storage Stability

EC Number Storage Stability Organism
4.1.1.112 4°C, phosphate buffer or arsenate buffer, pH 7, with mercaptoethanol, N2-atmosphere, 2 months Veillonella parvula

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.112 Oxaloacetate
-
 Veillonella parvula Pyruvate + CO2
-
 ?
4.1.1.112 oxaloacetate
-
 Veillonella parvula ?
-
 ?
4.1.1.112 Pyruvate + CO2
-
 Veillonella parvula Oxaloacetate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.112 37
-
 enzyme assay at Veillonella parvula

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.112 7
-
 enzyme assay at Veillonella parvula