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Literature summary extracted from
- Further studies of glutamic acid decarboxylase in brain (1951), J. Biol. Chem., 190, 505-512.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.15 | 2-oxoglutarate | - |
Mus musculus |  |
| 4.1.1.15 | D-Glu | - |
Mus musculus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.15 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.1.1.15 | brain | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.15 | L-Glu | - |
Mus musculus | 4-Aminobutanoate + CO2 | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.15 | 6.4 | 6.5 | - |
Mus musculus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.15 | 6 | 7.5 | pH 6.0: about 80% of maximal activity, pH 7.5: about 65% of maximal activity | Mus musculus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.15 | pyridoxal 5'-phosphate | highly specific as coenzyme | Mus musculus | |
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Release 2023.1 (January 2023)
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