EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.5 | EDTA | 93% inhibition at 1 mM | Mycolicibacterium phlei | |
2.2.1.5 | iodoacetic acid | 83% inhibition at 3.3 mM | Mycolicibacterium phlei | |
2.2.1.5 | p-chloromercuriphenylsulfonic acid | complete inhibition at 1 mM | Mycolicibacterium phlei | |
2.2.1.5 | Zn2+ | 97% inhibition at 1 mM | Mycolicibacterium phlei |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.2.1.5 | 2 | - |
2-oxoglutarate | - |
Mycolicibacterium phlei | |
2.2.1.5 | 3.2 | - |
glyoxylate | - |
Mycolicibacterium phlei |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.5 | Mg2+ | 31% activation at 1 mM | Mycolicibacterium phlei | |
2.2.1.5 | Mn2+ | 175% activation at 1 mM | Mycolicibacterium phlei |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.2.1.5 | Mycolicibacterium phlei | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.2.1.5 | - |
Mycolicibacterium phlei |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.2.1.5 | 2-oxoglutarate + glyoxylate = 2-hydroxy-3-oxoadipate + CO2 | mechanism | Mycolicibacterium phlei |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.2.1.5 | 2.21 | - |
- |
Mycolicibacterium phlei |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.2.1.5 | 2-oxoglutarate | - |
Mycolicibacterium phlei | ? + CO2 | - |
? | |
2.2.1.5 | 2-oxoglutarate + acetaldehyde | - |
Mycolicibacterium phlei | 5-hydroxy-4-oxohexanoate + CO2 | - |
? | |
2.2.1.5 | 2-oxoglutarate + glyoxylate | - |
Mycolicibacterium phlei | 2-hydroxy-3-oxohexandioate + CO2 | further spontaneous decarboxylation in the presence of acid | ? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.2.1.5 | 37 | - |
enzyme assay at | Mycolicibacterium phlei |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.2.1.5 | 6.3 | - |
- |
Mycolicibacterium phlei |
2.2.1.5 | 6.5 | - |
enzyme assay at | Mycolicibacterium phlei |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.5 | thiamine diphosphate | - |
Mycolicibacterium phlei |