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Literature summary extracted from

  • Phalip, V.; Schmitt, P.; Divies, C.
    Purification and characterization of the catabolic alpha-acetolactate synthase from Leuconostoc mesenteroides subsp. cremonis (1995), Curr. Microbiol., 31, 316-321.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.2.1.6 acetate increases activity Leuconostoc mesenteroides
2.2.1.6 ethanol increases activity Leuconostoc mesenteroides

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.2.1.6 3-phosphoglycerate noncompetitive Leuconostoc mesenteroides
2.2.1.6 ATP noncompetitive Leuconostoc mesenteroides
2.2.1.6 phosphoenolpyruvate noncompetitive Leuconostoc mesenteroides

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.2.1.6 10
-
 pyruvate
-
 Leuconostoc mesenteroides

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.2.1.6 additional information the enzyme does not require a divalent cation for activity Leuconostoc mesenteroides

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.2.1.6 55000
-
 3 * 55000, SDS-PAGE Leuconostoc mesenteroides
2.2.1.6 150000
-
-
 Leuconostoc mesenteroides

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.2.1.6 pyruvate Leuconostoc mesenteroides catabolic enzyme is involved in 2,3-butanediol pathway ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.6 Leuconostoc mesenteroides
-
 subsp. cremonis
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.2.1.6
-
 Leuconostoc mesenteroides

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.2.1.6 0.844
-
-
 Leuconostoc mesenteroides

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.2.1.6 pyruvate
-
 Leuconostoc mesenteroides 2-acetolactate + CO2
-
 ?
2.2.1.6 pyruvate catabolic enzyme is involved in 2,3-butanediol pathway Leuconostoc mesenteroides ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.2.1.6 trimer 3 * 55000, SDS-PAGE Leuconostoc mesenteroides

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.2.1.6 5.3
-
-
 Leuconostoc mesenteroides