EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.12 | 2-Oxo-5-carbamidopentanoate | activates | Alcaligenes faecalis | |
4.1.1.12 | 2-oxo-5-guanidinopentanoate | activates | Alcaligenes faecalis | |
4.1.1.12 | 2-oxoglutarate | activates | Alcaligenes faecalis | |
4.1.1.12 | 2-oxoglutarate | activates | Achromobacter sp. | |
4.1.1.12 | 2-oxoglutarate | activates | Pseudomonas dacunhae | |
4.1.1.12 | 2-Oxoisohexanoate | activates | Alcaligenes faecalis | |
4.1.1.12 | 2-oxoisopentanoate | activates | Alcaligenes faecalis | |
4.1.1.12 | 2-Oxomalonate | activates | Alcaligenes faecalis | |
4.1.1.12 | 2-oxophenylacetate | activates | Alcaligenes faecalis | |
4.1.1.12 | beta-cyano-L-Ala | competitive towards L-Asp | Alcaligenes faecalis | |
4.1.1.12 | D-2-Oxo-3-methylpentanoate | activates | Alcaligenes faecalis | |
4.1.1.12 | glyoxylate | activates | Alcaligenes faecalis | |
4.1.1.12 | glyoxylate | activates | Achromobacter sp. | |
4.1.1.12 | L-2-Oxo-3-methylpentanoate | activates | Alcaligenes faecalis | |
4.1.1.12 | additional information | interacts with a number of vitamin B6 5'-phosphate analogues | Alcaligenes faecalis | |
4.1.1.12 | phenylpyruvate | activates | Alcaligenes faecalis | |
4.1.1.12 | pyruvate | activates | Alcaligenes faecalis | |
4.1.1.12 | pyruvate | activates | Achromobacter sp. |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.1.12 | 0.024 | - |
erythro-beta-hydroxyaspartate | - |
Alcaligenes faecalis | |
4.1.1.12 | 0.063 | - |
beta-chloro-L-Ala | - |
Alcaligenes faecalis | |
4.1.1.12 | 0.089 | - |
threo-beta-hydroxyaspartate | - |
Alcaligenes faecalis | |
4.1.1.12 | 0.68 | - |
L-Asp | - |
Alcaligenes faecalis | |
4.1.1.12 | 3 | - |
aminomalonate | - |
Alcaligenes faecalis | |
4.1.1.12 | 4.8 | - |
L-cysteinesulfinate | - |
Alcaligenes faecalis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.12 | Acetobacter sp. | - |
- |
- |
4.1.1.12 | Achromobacter sp. | - |
- |
- |
4.1.1.12 | Alcaligenes faecalis | - |
- |
- |
4.1.1.12 | Astacoidea | - |
- |
- |
4.1.1.12 | Bombyx mori | - |
- |
- |
4.1.1.12 | Clostridium perfringens | - |
- |
- |
4.1.1.12 | Desulfovibrio desulfuricans | - |
- |
- |
4.1.1.12 | Lobster | - |
- |
- |
4.1.1.12 | Nocardia globerula | - |
- |
- |
4.1.1.12 | Pseudomonas dacunhae | - |
- |
- |
4.1.1.12 | Pseudomycobacteria | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.12 | Aminomalonate | - |
Alcaligenes faecalis | Gly + CO2 | - |
? | |
4.1.1.12 | beta-chloro-L-Ala + H2O | - |
Alcaligenes faecalis | pyruvate + Cl- + NH4+ | - |
? | |
4.1.1.12 | erythro-beta-Hydroxyaspartate | - |
Alcaligenes faecalis | L-Ser + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Alcaligenes faecalis | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Bombyx mori | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Achromobacter sp. | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Nocardia globerula | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Pseudomonas dacunhae | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Pseudomycobacteria | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Clostridium perfringens | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Desulfovibrio desulfuricans | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Acetobacter sp. | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Astacoidea | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Asp | - |
Lobster | L-Ala + CO2 | - |
? | |
4.1.1.12 | L-Cysteinesulfinate | - |
Alcaligenes faecalis | L-Ala + SO2 | - |
? | |
4.1.1.12 | L-Cysteinesulfinate | - |
Pseudomonas dacunhae | L-Ala + SO2 | - |
? | |
4.1.1.12 | additional information | - |
Pseudomonas dacunhae | ? | - |
? | |
4.1.1.12 | additional information | transamination between L-Asp and pyruvate | Alcaligenes faecalis | ? | - |
? | |
4.1.1.12 | threo-beta-Hydroxyaspartate | - |
Alcaligenes faecalis | L-Ser + CO2 | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.12 | pyridoxal 5'-phosphate | - |
Alcaligenes faecalis | |
4.1.1.12 | pyridoxal 5'-phosphate | - |
Achromobacter sp. | |
4.1.1.12 | pyridoxal 5'-phosphate | activates | Pseudomonas dacunhae | |
4.1.1.12 | pyridoxal 5'-phosphate | activates | Clostridium perfringens |