Literature summary extracted from

Musso, T.; Gusella, G.L.; Brooks, A.; Longo, D.L.; Varesio, L.
Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes (1994), Blood, 83, 1408-1411.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.13.11.52	L-Trp + O2	Homo sapiens	interleukin-4 inhibits expression of the enzyme in monocytes	L-formylkynurenine	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.52	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.52	monocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.52	L-Trp + O2	-	Homo sapiens	L-formylkynurenine	-	?
1.13.11.52	L-Trp + O2	interleukin-4 inhibits expression of the enzyme in monocytes	Homo sapiens	L-formylkynurenine	-	?

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Release 2023.1 (January 2023)