EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.13.11.52 | methylene blue | acts as electron mediator from donors to the ferric dioxygenase | Oryctolagus cuniculus | |
1.13.11.52 | additional information | the enzyme can be activated through different pathways either by superoxide anion or by an electron donor-methylene blue system where the dye is acting as an electron mediator from the donor to the ferric dioxygenase | Oryctolagus cuniculus | |
1.13.11.52 | O2- | - |
Oryctolagus cuniculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.13.11.52 | n-butyl isocyanide | heme ligand which binds tightly to the ferrous enzyme | Oryctolagus cuniculus | |
1.13.11.52 | Superoxide dismutase | 80-98% inhibition | Oryctolagus cuniculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.52 | L-tryptophan + O2 | Oryctolagus cuniculus | - |
N-formyl-L-kynurenine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.13.11.52 | Oryctolagus cuniculus | - |
- |
- |
EC Number | Oxidation Stability | Organism |
---|---|---|
1.13.11.52 | leuco-methylene blue reduces ferric enzyme | Oryctolagus cuniculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.13.11.52 | small intestine | - |
Oryctolagus cuniculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.52 | D-tryptophan + O2 | - |
Oryctolagus cuniculus | N-formyl-D-kynurenine | - |
? | |
1.13.11.52 | L-Trp + O2 | - |
Oryctolagus cuniculus | L-formylkynurenine | - |
? | |
1.13.11.52 | L-tryptophan + O2 | - |
Oryctolagus cuniculus | N-formyl-L-kynurenine | - |
? |