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Literature summary extracted from
- Heterogeneity among the flavin-containing NADH peroxidases of group D streptococci. Analysis of the enzyme from Streptococcus faecalis ATCC 9790 (1990), J. Biol. Chem., 265, 9857-9863.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.11.1.1 | Ethyl hydroperoxide | - |
Enterococcus faecalis |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.11.1.1 | 0.0025 | - |
NADH | - |
Enterococcus faecalis | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.11.1.1 | NADH + H2O2 | Enterococcus faecalis | elimination of toxic H2O2, regeneration of oxidized pyridine nucleotide which is essential to the strictly fermentative metabolism | NAD+ + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.11.1.1 | Enterococcus faecalis | - |
Enterococcus hirae | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.11.1.1 | - |
Enterococcus faecalis |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.11.1.1 | 86 | - |
- |
Enterococcus faecalis |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 1.11.1.1 | -20°C, 50 mM phosphate buffer pH 7.0 | Enterococcus faecalis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.11.1.1 | NADH + H2O2 | elimination of toxic H2O2, regeneration of oxidized pyridine nucleotide which is essential to the strictly fermentative metabolism | Enterococcus faecalis | NAD+ + H2O | - |
? | |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.11.1.1 | 5.4 | - |
45 min stable | Enterococcus faecalis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.11.1.1 | FAD | enzyme contains flavin and non-flavin redox centers | Enterococcus faecalis | |
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Release 2023.1 (January 2023)
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