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Literature summary extracted from

  • Pummill, P.E.; Achyuthan, A.M.; DeAngelis, P.L.
    Enzymological characterization of recombinant Xenopus DG42, a vertebrate hyaluronan synthase (1998), J. Biol. Chem., 273, 4976-4981.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.212 expression in yeast Xenopus laevis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.212 0.06
-
 UDP-D-glucuronate
-
 Xenopus laevis
2.4.1.212 0.23
-
 UDP-N-acetyl-D-glucosamine
-
 Xenopus laevis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.212 Mg2+
-
 Xenopus laevis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.212 UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate Xenopus laevis
-
 [beta-N-acetyl-D-glucosaminyl(1-4)beta-D-glucuronosyl(1-3)]n + UDP
-
 ?
2.4.1.212 UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate Xenopus laevis protein DG42
-
 [beta-N-acetyl-D-glucosaminyl(1-4)beta-D-glucuronosyl(1-3)]n + UDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.212 Xenopus laevis
-
-
-
2.4.1.212 Xenopus laevis protein DG42
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.212 UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate
-
 Xenopus laevis [beta-N-acetyl-D-glucosaminyl(1-4)beta-D-glucuronosyl(1-3)]n + UDP
-
 ?
2.4.1.212 UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate
-
 Xenopus laevis protein DG42 [beta-N-acetyl-D-glucosaminyl(1-4)beta-D-glucuronosyl(1-3)]n + UDP
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.212 7.6 8.1
-
 Xenopus laevis

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.1.212 7 8.4
-
 Xenopus laevis