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Literature summary extracted from

  • Itano, N.; Sawai, T.; Yoshida, M.; Lenas, P.; Yamada, Y.; Imagawa, M.; Shinomura, T.; Hamaguchi, M.; Yoshida, Y.; Ohnuki, Y.; Miyauchi, S.; Spicer, A.P.; McDonald, J.A.; Kimata, K.
    Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties (1999), J. Biol. Chem., 274, 25085-25092.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.212 expression in COS-1 cells and rat 3Y1 fibroblasts Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.212 additional information
-
 additional information values for other substrate concentrations Mus musculus
2.4.1.212 0.032
-
 UDP-D-glucuronate HAS2 Mus musculus
2.4.1.212 0.034
-
 UDP-D-glucuronate HAS3 Mus musculus
2.4.1.212 0.073
-
 UDP-D-glucuronate HAS1 Mus musculus
2.4.1.212 0.08
-
 UDP-N-acetyl-D-glucosamine HAS3 Mus musculus
2.4.1.212 0.11
-
 UDP-N-acetyl-D-glucosamine HAS2 Mus musculus
2.4.1.212 0.79
-
 UDP-N-acetyl-D-glucosamine HAS1 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.212 membrane
-
 Mus musculus 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.212 UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate Mus musculus
-
 [beta-N-acetyl-D-glucosaminyl(1-4)beta-D-glucuronosyl(1-3)]n + UDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.212 Mus musculus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.212 UDP-N-acetyl-D-glucosamine + UDP-D-glucuronate
-
 Mus musculus [beta-N-acetyl-D-glucosaminyl(1-4)beta-D-glucuronosyl(1-3)]n + UDP
-
 ?