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Literature summary extracted from

  • Lam, K.W.; Wang, L.; Hong, B.S.; Treble, D.
    Purification of phospholipid hydroperoxide glutathione peroxidase from bovine retina (1993), Curr. Eye Res., 12, 9-15.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.11.1.12 alpha-tocopherol complete inhibition of glutathione oxidation Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.11.1.12 0.011
-
 phospholipid hydroperoxide
-
 Bos taurus
1.11.1.12 1.37
-
 glutathione
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.11.1.12 particle-bound high-salt extract from retina Bos taurus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.11.1.12 Se
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.11.1.12 6000
-
 below, retina enzyme, gel filtration Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.12 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.11.1.12
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.1.12 retina
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.11.1.12 7
-
 purified enzyme Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.12 glutathione + cumene hydroperoxide no activity Bos taurus ?
-
 ?
1.11.1.12 glutathione + H2O2 no activity Bos taurus ?
-
 ?
1.11.1.12 glutathione + lipid hydroperoxide
-
 Bos taurus glutathione disulfide + lipid + H2O
-
 ?
1.11.1.12 glutathione + phospholipid hydroperoxide
-
 Bos taurus oxidized glutathione + phospholipid + H2O
-
 r
1.11.1.12 glutathione + phospholipid hydroperoxides
-
 Bos taurus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.11.1.12 monomer 1 * 6000, about, retina enzyme, SDS-PAGE Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.11.1.12 0.019
-
 alpha-tocopherol
-
 Bos taurus