Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Millard, S.A.; Kubose, A.; Gal, E.M.
    Brain lipoyl dehydrogenase. Purification, properties, and inhibitors (1969), J. Biol. Chem., 244, 2511-2515.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.1.4 2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine hydrochloride inhibition of NADH-lipoamide oxidoreductase activity, no effect on diaphorase activity and transhydrogenase activity Sus scrofa
1.8.1.4 2-amino-4-hydroxy-6,7-dimethyl-7,8-dihydropteridine inhibition of NADH-lipoamide oxidoreductase activity, no effect on diaphorase activity and transhydrogenase activity Sus scrofa
1.8.1.4 2-amino-4-hydroxy-6-methyl-7,8-dihydropteridine inhibition of NADH-lipoamide oxidoreductase activity, no effect on diaphorase activity and transhydrogenase activity Sus scrofa
1.8.1.4 folic acid inhibition of NADH-lipoamide oxidoreductase activity, no effect on diaphorase activity and transhydrogenase activity Sus scrofa
1.8.1.4 isobiopterin inhibition of NADH-lipoamide oxidoreductase activity, no effect on diaphorase activity and transhydrogenase activity Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.4 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.1.4
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.1.4 brain
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.8.1.4 77
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.4 dihydrolipoamide + NAD+
-
 Sus scrofa lipoamide + NADH
-
 ?
1.8.1.4 additional information diaphorase activity Sus scrofa ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.4 NAD+
-
 Sus scrofa