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Literature summary extracted from
- Identification of the prosthetic groups of dimethylamine dehydrogenase from Hyphomicrobium X (1979), Biochem. Biophys. Res. Commun., 88, 244-250.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.8.2 | diphosphate | noncompetitive inhibition to 50% of initial activity with respect to trimethylamine | Hyphomicrobium sp. |  |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.8.1 | Iron | contains 4.55 mol of iron and 3.91 mol of sulfur per mol of enzyme | Hyphomicrobium sp. | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.5.8.1 | 138000 | - |
gel filtration | Hyphomicrobium sp. |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.8.2 | trimethylamine + H2O + electron acceptor | Hyphomicrobium sp. | - |
dimethylamine + formaldehyde + reduced electron acceptor | - |
? | |
| 1.5.8.2 | trimethylamine + H2O + electron acceptor | Hyphomicrobium sp. X | - |
dimethylamine + formaldehyde + reduced electron acceptor | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.5.8.1 | Hyphomicrobium sp. | - |
X | - |
| 1.5.8.1 | Hyphomicrobium sp. X | - |
X | - |
| 1.5.8.2 | Hyphomicrobium sp. | - |
Hyphomicrobium X | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.5.8.1 | - |
Hyphomicrobium sp. |
| 1.5.8.2 | partial | Hyphomicrobium sp. |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.5.8.2 | cell culture | - |
Hyphomicrobium sp. | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.5.8.2 | 0.6 | - |
- |
Hyphomicrobium sp. |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.8.2 | trimethylamine + H2O + electron acceptor | - |
Hyphomicrobium sp. | dimethylamine + formaldehyde + reduced electron acceptor | - |
? | |
| 1.5.8.2 | trimethylamine + H2O + electron acceptor | - |
Hyphomicrobium sp. X | dimethylamine + formaldehyde + reduced electron acceptor | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.8.1 | 6-S-cysteinyl-FMN | contains 6-S-cysteinyl-FMN as coenzyme | Hyphomicrobium sp. | |
| 1.5.8.2 | FMN | 6-S-cysteinyl-FMN coenzyme-peptide | Hyphomicrobium sp. | |
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