Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kasprzak, A.A.; Papas, E.J.; Steenkamp, D.J.
    Identity of the subunits and the stoicheiometry of prosthetic groups in trimethylamine dehydrogenase and dimethylamine dehydrogenase (1983), Biochem. J., 211, 535-541.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.5.8.1 Iron each subunit contains a [4Fe-4S]cluster Hyphomicrobium sp.
1.5.8.2 Fe 4Fe-4S-center Methylophilus methylotrophus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus
-
 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein Hyphomicrobium sp.
-
 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus W3A1
-
 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein Hyphomicrobium sp. X
-
 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.8.1 Hyphomicrobium sp.
-
 X
-
1.5.8.1 Hyphomicrobium sp. X
-
 X
-
1.5.8.2 Hyphomicrobium sp.
-
 Hyphomicrobium X
-
1.5.8.2 Methylophilus methylotrophus
-
-
-
1.5.8.2 Methylophilus methylotrophus W3A1
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.8.2 cell culture
-
 Methylophilus methylotrophus
-
1.5.8.2 cell culture
-
 Hyphomicrobium sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein
-
 Methylophilus methylotrophus dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein
-
 Hyphomicrobium sp. dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein
-
 Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein
-
 Hyphomicrobium sp. X dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?

Subunits

EC Number Subunits Comment Organism
1.5.8.1 ? x * 70000-80000, SDS-PAGE, disc PAGE in presence of 8 M urea, after carboxymethylation Hyphomicrobium sp.
1.5.8.2 dimer molar absorption coefficient analysis Methylophilus methylotrophus
1.5.8.2 dimer molar absorption coefficient analysis Hyphomicrobium sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.8.1 6-S-cysteinyl-FMN each subunit contains a covalently bound 6-S-cysteinyl-FMN Hyphomicrobium sp.
1.5.8.2 FMN
-
 Methylophilus methylotrophus