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Literature summary extracted from

  • Deutch, C.E.; Klarstrom, J.L.; Link, C.L.; Ricciardi, D.L.
    Oxidation of L-thiazolidine-4-carboxylate by DELTA1-pyrroline-5-carboxylate reductase in Escherichia coli (2001), Curr. Microbiol., 42, 442-446.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.1.2 thiazolidine-4-carboxylic acid 42% inhibition at 10 mM, L-isomer Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5.1.2 0.03
-
 NADPH
-
 Escherichia coli
1.5.1.2 0.23
-
 NADH
-
 Escherichia coli
1.5.1.2 0.34
-
 DL-pyrroline-5-carboxylate
-
 Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.2 Escherichia coli
-
 K-12
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.5.1.2 copurification with thiazolidine-4-carboxylate dehydrogenase Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.5.1.2 15.9
-
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.2 1-pyrroline-5-carboxylate + NADH + H+
-
 Escherichia coli L-proline + NAD+
-
 r
1.5.1.2 3,4-dehydro-DL-proline + NADPH
-
 Escherichia coli ?
-
 ?