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Literature summary extracted from

  • Yura, T.; Vogel, H.J.
    Pyrroline-5-carboxylate reductase of Neurospora crassa: partial purification and some properties (1959), J. Biol. Chem., 234, 335-338.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5.1.2 additional information
-
 additional information
-
 Neurospora crassa
1.5.1.2 0.45
-
 1-pyrroline-5-carboxylate with NADPH Neurospora crassa
1.5.1.2 0.53
-
 1-pyrroline-5-carboxylate with NADH Neurospora crassa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.5.1.2 soluble
-
 Neurospora crassa
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.2 pyrroline-5-carboxylate + NAD(P)H + H+ Escherichia coli
-
 L-proline + NAD(P)+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.2 Escherichia coli
-
-
-
1.5.1.2 Neurospora crassa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.5.1.2 partial Neurospora crassa

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.5.1.2 additional information
-
 various growth stages Neurospora crassa
1.5.1.2 615
-
-
 Neurospora crassa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.2 1-pyrroline-5-carboxylate + NAD(P)H + H+
-
 Escherichia coli L-proline + NAD(P)+
-
 ?
1.5.1.2 1-pyrroline-5-carboxylate + NAD(P)H + H+
-
 Neurospora crassa L-proline + NAD(P)+
-
 ?
1.5.1.2 1-pyrroline-5-carboxylate + NADH + H+
-
 Neurospora crassa L-proline + NAD+
-
 r
1.5.1.2 1-pyrroline-5-carboxylate + NADPH + H+
-
 Neurospora crassa L-proline + NADP+
-
 r
1.5.1.2 pyrroline-5-carboxylate + NAD(P)H + H+
-
 Escherichia coli L-proline + NAD(P)+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.5.1.2 6
-
 cofactor NADH Neurospora crassa
1.5.1.2 7
-
 cofactor NADPH Neurospora crassa

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.2 NADH preferentially Escherichia coli
1.5.1.2 NADH preferentially Neurospora crassa
1.5.1.2 NADPH
-
 Escherichia coli
1.5.1.2 NADPH
-
 Neurospora crassa