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Literature summary extracted from

  • Nemat-Gorgani, M.; Dodd, G.
    The interaction of phospholipid membranes and detergents with glutamate dehydrogenase (1977), Eur. J. Biochem., 74, 129-137.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.1.3 cardiolipin
-
 Bos taurus
1.4.1.3 phosphatidylserine assumed to be a simple non-competitive inhibition Bos taurus
1.4.1.3 sodium dodecylsulfate time-dependent irreversible inhibition, 0.2 mM, 37% inhibition, 0.15 mM, 50% inhibition after 30 min, in the presence of 2-oxoglutarate after 370 min Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.1.3 3.2
-
 NH4+
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.3 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.1.3 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.1.3 L-glutamate + H2O + NAD(P)+
-
 Bos taurus 2-oxoglutarate + NH3 + NAD(P)H
-
 r

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.4.1.3 37
-
 complete loss of activity Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4.1.3 0.0009 0.061 phosphatidylserine
-
 Bos taurus