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Literature summary extracted from

  • Misono, H.; Nagasaki, S.
    Occurrence of L-lysine epsilon-dehydrogenase in Agrobacterium tumefaciens (1982), J. Bacteriol., 150, 398-401.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.1.15 L-lysine + NAD+ + H2O Agrobacterium tumefaciens epsilon amino group is oxidatively deaminated to alpha-aminoadipate delta-semialdehyde, which is spontaneously converted into 1,2-didehydropiperidine-6-carboxylate, first step of lysine degradation 1,2-didehydropiperidine-6-carboxylate + NH3 + NADH
-
 ?
1.4.1.18 L-lysine + NAD+ + H2O Agrobacterium tumefaciens
-
 alpha-aminoadipate delta-semialdehyde + NH3 + NADH product is spontaneosly converted into delta1-piperideine-6-carboxylate ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.15 Agrobacterium tumefaciens
-
-
-
1.4.1.18 Agrobacterium tumefaciens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.1.18
-
 Agrobacterium tumefaciens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.1.15 L-lysine + NAD+ + H2O epsilon amino group is oxidatively deaminated to alpha-aminoadipate delta-semialdehyde, which is spontaneously converted into 1,2-didehydropiperidine-6-carboxylate Agrobacterium tumefaciens 1,2-didehydropiperidine-6-carboxylate + NH3 + NADH
-
 ?
1.4.1.15 L-lysine + NAD+ + H2O epsilon amino group is oxidatively deaminated to alpha-aminoadipate delta-semialdehyde, which is spontaneously converted into 1,2-didehydropiperidine-6-carboxylate, first step of lysine degradation Agrobacterium tumefaciens 1,2-didehydropiperidine-6-carboxylate + NH3 + NADH
-
 ?
1.4.1.18 L-lysine + NAD+ + H2O
-
 Agrobacterium tumefaciens alpha-aminoadipate delta-semialdehyde + NH3 + NADH product is spontaneosly converted into delta1-piperideine-6-carboxylate ?

Synonyms

EC Number Synonyms Comment Organism
1.4.1.15 L-lysine epsilon dehydrogenase
-
 Agrobacterium tumefaciens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.4.1.15 9.7
-
-
 Agrobacterium tumefaciens
1.4.1.18 9.7
-
-
 Agrobacterium tumefaciens

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.1.15 NAD+ NADP+ can not replace NAD+ Agrobacterium tumefaciens
1.4.1.18 NAD+
-
 Agrobacterium tumefaciens