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Literature summary extracted from

  • Hsu, W.P.; Miller, G.W.
    Coproporphyrinogenase in tobacco (Nicotiana tabacum L.) (1970), Biochem. J., 117, 215-220.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.3.3 1,10-phenanthroline inhibition at 1 mM Nicotiana tabacum
1.3.3.3 Co2+ inhibition above 5 mM Nicotiana tabacum
1.3.3.3 Cu2+ inhibition at 0.1 mM Nicotiana tabacum
1.3.3.3 EDTA inhibition at 1 mM Nicotiana tabacum
1.3.3.3 Fe2+ inhibition above 0.1 mM Nicotiana tabacum
1.3.3.3 Mn2+ inhibition above 5 mM Nicotiana tabacum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.3.3 0.036
-
 Coproporphyrinogen-III
-
 Nicotiana tabacum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.3.3 mitochondrion
-
 Nicotiana tabacum 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.3.3.3 Co2+ activation up to 0.1 mM, beyond inhibitory Nicotiana tabacum
1.3.3.3 Fe2+ enhanced activity by increasing concentrations up to 0.5 mM, beyond inhibitory Nicotiana tabacum
1.3.3.3 Mn2+ activation up to 0.1 mM, beyond inhibitory Nicotiana tabacum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.3.3 coproporphyrinogen-III + O2 + 2 H+ Nicotiana tabacum
-
 protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.3.3 Nicotiana tabacum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.3.3 69fold purificationcalcium phosphate gel Nicotiana tabacum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.3.3 leaf
-
 Nicotiana tabacum
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3.3.3 0.002
-
-
 Nicotiana tabacum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.3 coproporphyrinogen-III + O2 + 2 H+
-
 Nicotiana tabacum protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
 ?