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Literature summary extracted from

  • Tait, G.H.
    Coproporphyrinogenase activities in extracts of Rhodopseudomonas spheroids (1976), Biochem. J., 118, 28P-29P.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.3.3 1,10-phenanthroline 90% inhibition of anaerobic reaction at 0.17 mM Cereibacter sphaeroides
1.3.3.3 2,2-bipyridyl 77% inhibition of anaerobic reaction at 1.5 mM Cereibacter sphaeroides
1.3.3.3 2,4-dinitrophenol 90% inhibition of anaerobic reaction at 0.7 mM Cereibacter sphaeroides
1.3.3.3 FAD 95% inhibition of anaerobic reaction at 0.03 mM Cereibacter sphaeroides
1.3.3.3 FMN 95% inhibition of anaerobic reaction at 0.03 mM Cereibacter sphaeroides
1.3.3.3 riboflavin 95% inhibition of anaerobic reaction at 0.03 mM Cereibacter sphaeroides

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.3.3 coproporphyrinogen-III + 2 NADP+ Cereibacter sphaeroides oxidation under anaerobic conditions strictly requires NADP+ as electron acceptor protoporphyrinogen-IX + 2 CO2 + 2 NADPH + 2 H+
-
 ?
1.3.3.3 coproporphyrinogen-III + ? Cereibacter sphaeroides anaerobic enzyme, presence of Mg2+, L-Met, ATP, NADH and NADP+ protoporphyrinogen-IX + ?
-
 ?
1.3.3.3 coproporphyrinogen-III + O2 + 2 H+ Cereibacter sphaeroides
-
 protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.3.3 Cereibacter sphaeroides
-
-
-

Oxidation Stability

EC Number Oxidation Stability Organism
1.3.3.3 succinate protects against oxidation Cereibacter sphaeroides

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.3.3 cell culture
-
 Cereibacter sphaeroides
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.3 coproporphyrinogen-III + 2 NADP+ oxidation under anaerobic conditions strictly requires NADP+ as electron acceptor Cereibacter sphaeroides protoporphyrinogen-IX + 2 CO2 + 2 NADPH + 2 H+
-
 ?
1.3.3.3 coproporphyrinogen-III + ? anaerobic enzyme, presence of Mg2+, L-Met, ATP, NADH and NADP+ Cereibacter sphaeroides protoporphyrinogen-IX + ?
-
 ?
1.3.3.3 coproporphyrinogen-III + O2 + 2 H+
-
 Cereibacter sphaeroides protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.3.3 7
-
 aerobic reaction Cereibacter sphaeroides
1.3.3.3 8.5
-
 anaerobic reaction Cereibacter sphaeroides

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.3.3 ATP strictly required for anaerobic enzyme Cereibacter sphaeroides
1.3.3.3 NAD+ only anaerobic enzyme, slightly less active than NADP+ Cereibacter sphaeroides
1.3.3.3 NADP+ only anaerobic enzyme, maximum activity together with NADH Cereibacter sphaeroides