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Literature summary extracted from

  • Robinson, J.A.; McDonald, E.; Battersby, A.R.
    Biosynthesis of porphyrins and related macrocycles. Part 25. Synthesis of analogues of coproporphyrinogen-III and studies of their interaction with coproporphyrinogen-III oxidase from Euglena gracilis (1985), J. Chem. Soc. Perkin Trans. I, 1985, 1699-1709.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.3.3 coproporphyrinogen-III + O2 + 2 H+ Euglena gracilis acts on analogues which possess normal substituents on ring-A to generate a vinyl group on that ring, not active if the ring-A propionate group is changed protoporphyrinogen-IX + 2 CO2 + 2 H2O
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Organism

EC Number Organism UniProt Comment Textmining
1.3.3.3 Euglena gracilis
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.3.3 cell culture
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Euglena gracilis
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.3 17-(3-carboxypropyl)-5,10,15,20,22,24-hexahydro-3,7,13,18-tetramethyl-21H,23H-porphine-2,8,12-tripropanoic acid + O2 generates a vinyl group on ring-A Euglena gracilis ? + CO2
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1.3.3.3 5,10,15,20,22,24-hexahydro-3,7,13,18-tetramethyl-21H,23H-porphine-2,8,12,17-tripropanoic acid 17-methyl ester + O2 very poor substrate Euglena gracilis ? + CO2
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1.3.3.3 coproporphyrinogen-III + O2 + 2 H+ acts on analogues which possess normal substituents on ring-A to generate a vinyl group on that ring, not active if the ring-A propionate group is changed Euglena gracilis protoporphyrinogen-IX + 2 CO2 + 2 H2O
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