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Literature summary extracted from

  • Rippert, P.; Matringe, M.
    Molecular and biochemical characterization of an Arabidopsis thaliana arogenate dehydrogenase with two highly similar and active protein domains (2002), Plant Mol. Biol., 48, 361-368.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.1.78 tyrA gene, overexpression in Escherichia coli, 3 different plasmids TyrA-ATcM36, TyrA-ATlM36, TyrA-AT2 Arabidopsis thaliana

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.78 L-tyrosine
-
 Arabidopsis thaliana

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.1.78 0.02
-
 NADP+ recombinant from plasmid TyrA-AT2 Arabidopsis thaliana
1.3.1.78 0.04
-
 NADP+ recombinant from plasmid TyrA-ATcM36 Arabidopsis thaliana
1.3.1.78 0.045
-
 L-arogenate recombinant from plasmids TyrA-AT2 and TyrA-ATlM36 Arabidopsis thaliana
1.3.1.78 0.07
-
 L-arogenate recombinant from plasmid TyrA-ATcM36 Arabidopsis thaliana
1.3.1.78 0.075
-
 NADP+ recombinant from plasmid TyrA-ATlM36 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.78 L-arogenate + NAD+ Arabidopsis thaliana
-
 L-tyrosine + NADH + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.78 Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.78 L-arogenate + NAD(P)+
-
 Arabidopsis thaliana L-tyrosine + NAD(P)H + CO2
-
 ?
1.3.1.78 L-arogenate + NAD+
-
 Arabidopsis thaliana L-tyrosine + NADH + CO2
-
 ?
1.3.1.78 prephenate + NAD(P)+ not prephenate Arabidopsis thaliana ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.78 cyclohexadienyl dehydrogenase
-
 Arabidopsis thaliana

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.3.1.78 25
-
 assay at Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.78 NAD+
-
 Arabidopsis thaliana
1.3.1.78 NADP+
-
 Arabidopsis thaliana

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.3.1.78 0.008
-
 L-tyrosine recombinant from plasmid TyrA-ATlM36 Arabidopsis thaliana
1.3.1.78 0.012
-
 L-tyrosine recombinant from plasmid TyrA-AT2 Arabidopsis thaliana
1.3.1.78 0.014
-
 L-tyrosine recombinant from plasmid TyrA-ATcM36 Arabidopsis thaliana