EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.93 | Tartronate | inhibition of oxidative decarboxylation of D-malate | Pseudomonas putida |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.93 | 0.024 | - |
(2R,3R)-3-iodomalate | - |
Pseudomonas putida |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.93 | Pseudomonas putida | - |
enzyme expressed in Escherichia coli carrying the plasmid pTDH1, which expresses the gene encoding TDH at high levels | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.93 | (2R,3R)-3-iodomalate + NAD+ | - |
Pseudomonas putida | 3-iodopyruvate + NADH + CO2 | - |
? | |
1.1.1.93 | D-malate + NAD+ | - |
Pseudomonas putida | pyruvate + CO2 + NADH | - |
? | |
1.1.1.93 | L-tartrate + NAD+ | - |
Pseudomonas putida | oxaloglycolate + NADH + H+ | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.93 | additional information | - |
additional information | D-malate oxidation is largely limited by the rate of decarboxylation of the intermediate oxaloacetate which occurs at 660 per min. Hydride transfer from D-malate to NAD+ occurs with a rate constant of 1800 per min | Pseudomonas putida |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.93 | NAD+ | cofactor | Pseudomonas putida |