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Literature summary extracted from

  • Suzuki-Yamamoto, T.; Toida, K.; Tsuruo, Y.; Watanabe, K.; Ishimura, K.
    Immunocytochemical localization of lung-type prostaglandin F synthase in the rat spinal cord (2000), Brain Res., 877, 391-395.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.188 cytosol
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 Rattus norvegicus 5829
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Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.188 36700
-
 Western blot with antibody staining Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.188 (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADPH Rattus norvegicus prostaglandin F2alpha exhibits contraction of smooth muscles in the uterus, brochus trachea, luteolysis, the initiation of partutition and pain transmission (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate + NADP+
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.188 Rattus norvegicus
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 two isozymes, lung-type and liver-type
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.188 spinal cord neuronal dendrites and somata of gray matter Rattus norvegicus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.188 (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADPH
-
 Rattus norvegicus (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate + NADP+
-
 ?
1.1.1.188 (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADPH prostaglandin F2alpha exhibits contraction of smooth muscles in the uterus, brochus trachea, luteolysis, the initiation of partutition and pain transmission Rattus norvegicus (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate + NADP+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.188 NADPH
-
 Rattus norvegicus