Any feedback?
Literature summary extracted from
- DNA topoisomerase II from Drosophila melanogaster. Purification and physical characterization (1983), J. Biol. Chem., 258, 9530-9535.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.6.2.2 | nucleus | - |
Drosophila melanogaster | 5634 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.6.2.2 | 166000 | - |
2 * 166000, SDS-PAGE | Drosophila melanogaster |
| 5.6.2.2 | 261000 | - |
gel filtration, glycerol density gradient centrifugation | Drosophila melanogaster |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.2.2 | Drosophila melanogaster | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.6.2.2 | - |
Drosophila melanogaster |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.2.2 | embryo | - |
Drosophila melanogaster | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.6.2.2 | additional information | - |
- |
Drosophila melanogaster |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 5.6.2.2 | 4°C, stable for at least one year | Drosophila melanogaster |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.2.2 | additional information | the following reactions are catalyzed in an ATP-dependent fashion: relaxation of superhelical turns, catenation, decatenation, unknotting of circular duplex DNA | Drosophila melanogaster | ? | - |
? |  |
| 5.6.2.2 | network of DNA rings + ATP + H2O | decatenation | Drosophila melanogaster | monomeric DNA circles + ADP + phosphate | - |
? | |
| 5.6.2.2 | supercoiled DNA + ATP + H2O | catenation | Drosophila melanogaster | catenated DNA networks + ADP + phosphate | - |
? | |
| 5.6.2.2 | supercoiled DNA + ATP + H2O | catenation in presence of the condensing agent histone H1 | Drosophila melanogaster | catenated DNA networks + ADP + phosphate | - |
? | |
| 5.6.2.2 | supercoiled DNA + ATP + H2O | relaxation | Drosophila melanogaster | relaxed DNA + ADP + phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.6.2.2 | dimer | 2 * 166000, SDS-PAGE | Drosophila melanogaster |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
