EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.99.1 | 0.019 | - |
indole | - |
Escherichia coli | |
4.1.99.1 | 70 | - |
pyruvate | - |
Escherichia coli | |
4.1.99.1 | 345 | - |
NH4+ | - |
Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.99.1 | Escherichia coli | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
4.1.99.1 | L-tryptophan + H2O = indole + pyruvate + NH3 | in the reverse direction NH4+ interacts with bound pyridoxal 5'-phosphate to form an imine. Pyruvate is the second substrate, indole the third. alpha-Aminoacrylate functions as a common enzyme-bound intermediate in both synthetic and degradative reactions | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.99.1 | indole + pyruvate + NH4+ | - |
Escherichia coli | L-Trp + H2O | - |
? | |
4.1.99.1 | L-Trp + H2O | - |
Escherichia coli | indole + pyruvate + NH4+ | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.1.99.1 | 8.5 | - |
degradation of Trp | Escherichia coli |
4.1.99.1 | 9 | - |
synthesis of Trp | Escherichia coli |