Literature summary extracted from

Lazo, J.S.; Merrill, W.W.; Pham, E.T.; Lynch, T.J.; McCallister, J.D.; Ingbar, D.H.
Bleomycin hydrolase activity in pulmonary cells (1984), J. Pharmacol. Exp. Ther., 231, 583-588.

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
3.4.22.40	0.7	-	bleomycin A2	-	Bos taurus
3.4.22.40	0.7	-	bleomycin A2	-	Oryctolagus cuniculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.22.40	Bos taurus	-	-	-
3.4.22.40	Oryctolagus cuniculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.22.40	endothelium	-	Oryctolagus cuniculus	-
3.4.22.40	lung	-	Bos taurus	-
3.4.22.40	lung	-	Oryctolagus cuniculus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.22.40	bleomycin + H2O	bleomycin A2	Bos taurus	deamido-bleomycin	-	?
3.4.22.40	bleomycin + H2O	bleomycin A2	Oryctolagus cuniculus	deamido-bleomycin	-	?
3.4.22.40	bleomycin A2 + H2O	-	Bos taurus	?	-	?
3.4.22.40	bleomycin A2 + H2O	-	Oryctolagus cuniculus	?	-	?

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Release 2023.1 (January 2023)