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Literature summary extracted from
- Carboxypeptidasen (1974), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 1, 1023-1037.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.17.1 | 1,10-phenanthroline | - |
Bos taurus |  |
| 3.4.17.1 | 1,10-phenanthroline | - |
Homo sapiens | |
| 3.4.17.1 | 1,10-phenanthroline | - |
Rattus norvegicus | |
| 3.4.17.1 | citrate | - |
Bos taurus | |
| 3.4.17.1 | CN- | - |
Bos taurus | |
| 3.4.17.1 | Cu2+ | - |
Bos taurus | |
| 3.4.17.1 | Cys | - |
Bos taurus | |
| 3.4.17.1 | EDTA | - |
Bos taurus | |
| 3.4.17.1 | Fe3+ | - |
Bos taurus | |
| 3.4.17.1 | L-Phe | - |
Bos taurus | |
| 3.4.17.1 | P2O74- | - |
Bos taurus | |
| 3.4.17.1 | Pb2+ | - |
Bos taurus | |
| 3.4.17.1 | PO43- | - |
Bos taurus | |
| 3.4.17.1 | SH- | - |
Bos taurus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.17.1 | Cd2+ | - |
Homo sapiens | |
| 3.4.17.1 | Cd2+ | activates apoenzyme | Bos taurus | |
| 3.4.17.1 | Co2+ | - |
Homo sapiens | |
| 3.4.17.1 | Co2+ | activates apoenzyme | Bos taurus | |
| 3.4.17.1 | Mn2+ | - |
Homo sapiens | |
| 3.4.17.1 | Mn2+ | activates apoenzyme | Bos taurus | |
| 3.4.17.1 | Ni2+ | - |
Homo sapiens | |
| 3.4.17.1 | Ni2+ | activates apoenzyme | Bos taurus | |
| 3.4.17.1 | Zn2+ | - |
Homo sapiens | |
| 3.4.17.1 | Zn2+ | - |
Rattus norvegicus | |
| 3.4.17.1 | Zn2+ | activates apoenzyme | Bos taurus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.17.1 | Bos taurus | - |
overview, forms alpha, beta, gamma, and delta may result from slightly different activation conditions | - |
| 3.4.17.1 | Homo sapiens | - |
- |
- |
| 3.4.17.1 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.17.1 | heart | - |
Rattus norvegicus | - |
| 3.4.17.1 | liver | - |
Rattus norvegicus | - |
| 3.4.17.1 | pancreas | - |
Homo sapiens | - |
| 3.4.17.1 | pancreas | - |
Rattus norvegicus | - |
| 3.4.17.1 | pancreas | - |
Bos taurus | - |
| 3.4.17.1 | serum | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.17.1 | additional information | - |
- |
Bos taurus |
| 3.4.17.1 | additional information | - |
activity in fresh serum, liver, heart tissues | Homo sapiens |
| 3.4.17.1 | additional information | - |
activity in fresh serum, liver, heart tissues | Rattus norvegicus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.17.1 | 20 | - |
- |
Homo sapiens |
| 3.4.17.1 | 20 | - |
no measurements below | Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.17.1 | 7.4 | 7.8 | buffer-dependent, Tris better than phosphate buffer | Bos taurus |
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