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Literature summary extracted from

  • Itoh, C.; Nagamatsu, A.
    An aminopeptidase activity from porcine kidney that hydrolyzes oxytocin and vasopressin: purification and partial characterization (1995), Biochim. Biophys. Acta, 1243, 203-208.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.11.3 2-mercaptoethanol stimulates at 1 mM Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.3 1,10-phenanthroline
-
 Sus scrofa
3.4.11.3 2-mercaptoethanol inhibition above 1 mM Sus scrofa
3.4.11.3 amastatin
-
 Sus scrofa
3.4.11.3 bestatin
-
 Sus scrofa
3.4.11.3 cysteine
-
 Sus scrofa
3.4.11.3 EDTA slightly Sus scrofa
3.4.11.3 Ni2+
-
 Sus scrofa
3.4.11.3 p-chloromercuribenzoate
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.3 0.11
-
 S-benzyl-L-cysteine-p-nitroanilide
-
 Sus scrofa
3.4.11.3 0.15
-
 L-Leu-4-nitroanilide
-
 Sus scrofa
3.4.11.3 0.43
-
 L-Lysine-p-nitroanilide
-
 Sus scrofa
3.4.11.3 0.83
-
 L-methionine-p-nitroanilide
-
 Sus scrofa
3.4.11.3 1.43
-
 L-alanine-p-nitroanilide
-
 Sus scrofa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.3 Co2+ stimulates Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.3 104000
-
 1 * 104000, SDS-PAGE Sus scrofa
3.4.11.3 105000
-
 gel filtration Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.3 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.3
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.3 kidney
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.3 L-alanine-p-nitroanilide + H2O
-
 Sus scrofa L-alanine + p-nitroaniline
-
 ?
3.4.11.3 L-Leu-4-nitroanilide + H2O
-
 Sus scrofa L-Leu + 4-nitroaniline
-
 ?
3.4.11.3 L-lysine-p-nitroanilide + H2O
-
 Sus scrofa L-lysine + p-nitroaniline
-
 ?
3.4.11.3 L-methionine-p-nitroanilide + H2O
-
 Sus scrofa L-methionine + p-nitroaniline
-
 ?
3.4.11.3 S-benzyl-L-cysteine-p-nitroanilide + H2O
-
 Sus scrofa S-benzyl-L-cysteine + p-nitroaniline
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.11.3 monomer 1 * 104000, SDS-PAGE Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.3 7.8
-
-
 Sus scrofa