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Literature summary extracted from

  • Wojnarowska, F.; Gray, G.M.
    Intestinal surface peptide hydrolases: identification and characterization of three enzymes from rat brush border (1975), Biochim. Biophys. Acta, 403, 147-160.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 Co2+
-
 Rattus norvegicus
3.4.11.2 EDTA 100% inhibition at 5 mM Rattus norvegicus
3.4.11.2 Mg2+
-
 Rattus norvegicus
3.4.11.2 Mn2+
-
 Rattus norvegicus
3.4.11.2 Zn2+
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.2 0.06 0.076 Leu-Gly
-
 Rattus norvegicus
3.4.11.2 0.41 0.79 Leu-2-naphthylamide
-
 Rattus norvegicus
3.4.11.2 0.6 0.76 Leu-Gly
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.2 membrane brush border membrane Rattus norvegicus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.2 160000
-
 peptidase II, density gradient centrifugation Rattus norvegicus
3.4.11.2 230000
-
 peptidase I, density gradient centrifugation Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.11.2 aminoacyl peptide Rattus norvegicus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.2 2 isoenzymes Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.2 intestine
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 aminoacyl peptide
-
 Rattus norvegicus ?
-
 ?
3.4.11.2 aminoacyl peptide + H2O
-
 Rattus norvegicus alanyl peptides + H2O
-
 ?
3.4.11.2 dipeptides + H2O
-
 Rattus norvegicus amino acids
-
 ?
3.4.11.2 Leu-2-naphthylamide + H2O
-
 Rattus norvegicus Leu + 2-naphthylamine
-
 ?
3.4.11.2 Leu-Gly + H2O
-
 Rattus norvegicus Leu + Gly
-
 ?
3.4.11.2 tripeptides + H2O
-
 Rattus norvegicus dipeptides + amino acids
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.2 7.5
-
-
 Rattus norvegicus