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Literature summary extracted from

  • Okuda, M.; Kohno, H.; Furukawa, T.; Tokunaga, R.; Taketani, S.
    Overexpression in Escherichia coli, and one-step purification of the human recombinant ferrochelatase (1994), Biochim. Biophys. Acta, 1200, 123-128.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.98.1.1 overexpression in Escherichia coli Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.98.1.1 0.0067
-
 Fe2+
-
 Homo sapiens
4.98.1.1 0.0118
-
 Zn2+
-
 Homo sapiens
4.98.1.1 0.0125
-
 protoporphyrin
-
 Homo sapiens
4.98.1.1 0.0125
-
 mesoporphyrin
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.98.1.1 soluble
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.98.1.1 40000
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.98.1.1 protoporphyrin IX + Fe2+ Homo sapiens final step of heme biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.98.1.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.98.1.1 expressed in Escherichia coli Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.98.1.1 protoporphyrin + Fe2+
-
 Homo sapiens protoheme + 2 H+
-
 ?
4.98.1.1 protoporphyrin IX + Fe2+ final step of heme biosynthesis Homo sapiens ?
-
 ?