BRENDA - Enzyme Database

A further characterization of alanine dehydrogenase from Streptomyces aureofaciens

Vancurova, I.; Vancura, A.; Volc, J.; Neuzil, J.; Behal, V.; J. Basic Microbiol. 29, 185-189 (1989) View publication on PubMed

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.4.1.1
HgCl2
-
Kitasatospora aureofaciens
1.4.1.1
L-Ala
reductive amination of pyruvate
Kitasatospora aureofaciens
1.4.1.1
L-Ser
inhibition of aminating activity
Kitasatospora aureofaciens
1.4.1.1
PCMB
-
Kitasatospora aureofaciens
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
1.4.1.1
198000
-
analytical ultracentrifugation
Kitasatospora aureofaciens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
1.4.1.1
L-Ala + H2O + NAD+
Kitasatospora aureofaciens
physiological role in nitrogen metabolism in Streptomycetes
pyruvate + NH3 + NADH
-
-
?
Organism
EC Number
Organism
UniProt
Commentary
Textmining
1.4.1.1
Kitasatospora aureofaciens
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
1.4.1.1
L-Ala + H2O + 1,N6-etheno-NAD+
45% of the activity with NAD+
349546
Kitasatospora aureofaciens
pyruvate + NH3 + 1,N6-etheno-NADH
-
-
-
?
1.4.1.1
L-Ala + H2O + 3-acetylpyridine-NAD+
as active as NAD+
349546
Kitasatospora aureofaciens
pyruvate + H2O + 3-acetylpyridine-NADH
-
-
-
?
1.4.1.1
L-Ala + H2O + 3-pyridinealdehyde-NAD+
5.0% of the activity with NAD+
349546
Kitasatospora aureofaciens
?
-
-
-
?
1.4.1.1
L-Ala + H2O + deamino-NAD+
90.2% of the activity with NAD+
349546
Kitasatospora aureofaciens
pyruvate + NH3 + deamino-NADH
-
-
-
?
1.4.1.1
L-Ala + H2O + NAD+
-
349546
Kitasatospora aureofaciens
pyruvate + NH3 + NADH
-
349546
Kitasatospora aureofaciens
r
1.4.1.1
L-Ala + H2O + NAD+
physiological role in nitrogen metabolism in Streptomycetes
349546
Kitasatospora aureofaciens
pyruvate + NH3 + NADH
-
-
-
?
1.4.1.1
L-Ala + H2O + nicotinamide guanine dinucleotide
59.9% of the activity with NAD+
349546
Kitasatospora aureofaciens
?
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.4.1.1
1,N6-etheno-NAD+
45% of the activity with NAD+
Kitasatospora aureofaciens
1.4.1.1
3-acetylpyridine-NAD+
as active as NAD+
Kitasatospora aureofaciens
1.4.1.1
3-pyridinealdehyde-NAD+
5.0% of the activity with NAD+
Kitasatospora aureofaciens
1.4.1.1
deamino-NAD+
90.2% of the activity with NAD+
Kitasatospora aureofaciens
1.4.1.1
NAD+
-
Kitasatospora aureofaciens
1.4.1.1
NADH
-
Kitasatospora aureofaciens
1.4.1.1
nicotinamide guanine dinucleotide
59.9% of the activity with NAD+
Kitasatospora aureofaciens
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.4.1.1
1,N6-etheno-NAD+
45% of the activity with NAD+
Kitasatospora aureofaciens
1.4.1.1
3-acetylpyridine-NAD+
as active as NAD+
Kitasatospora aureofaciens
1.4.1.1
3-pyridinealdehyde-NAD+
5.0% of the activity with NAD+
Kitasatospora aureofaciens
1.4.1.1
deamino-NAD+
90.2% of the activity with NAD+
Kitasatospora aureofaciens
1.4.1.1
NAD+
-
Kitasatospora aureofaciens
1.4.1.1
NADH
-
Kitasatospora aureofaciens
1.4.1.1
nicotinamide guanine dinucleotide
59.9% of the activity with NAD+
Kitasatospora aureofaciens
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.4.1.1
HgCl2
-
Kitasatospora aureofaciens
1.4.1.1
L-Ala
reductive amination of pyruvate
Kitasatospora aureofaciens
1.4.1.1
L-Ser
inhibition of aminating activity
Kitasatospora aureofaciens
1.4.1.1
PCMB
-
Kitasatospora aureofaciens
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
1.4.1.1
198000
-
analytical ultracentrifugation
Kitasatospora aureofaciens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
1.4.1.1
L-Ala + H2O + NAD+
Kitasatospora aureofaciens
physiological role in nitrogen metabolism in Streptomycetes
pyruvate + NH3 + NADH
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
1.4.1.1
L-Ala + H2O + 1,N6-etheno-NAD+
45% of the activity with NAD+
349546
Kitasatospora aureofaciens
pyruvate + NH3 + 1,N6-etheno-NADH
-
-
-
?
1.4.1.1
L-Ala + H2O + 3-acetylpyridine-NAD+
as active as NAD+
349546
Kitasatospora aureofaciens
pyruvate + H2O + 3-acetylpyridine-NADH
-
-
-
?
1.4.1.1
L-Ala + H2O + 3-pyridinealdehyde-NAD+
5.0% of the activity with NAD+
349546
Kitasatospora aureofaciens
?
-
-
-
?
1.4.1.1
L-Ala + H2O + deamino-NAD+
90.2% of the activity with NAD+
349546
Kitasatospora aureofaciens
pyruvate + NH3 + deamino-NADH
-
-
-
?
1.4.1.1
L-Ala + H2O + NAD+
-
349546
Kitasatospora aureofaciens
pyruvate + NH3 + NADH
-
349546
Kitasatospora aureofaciens
r
1.4.1.1
L-Ala + H2O + NAD+
physiological role in nitrogen metabolism in Streptomycetes
349546
Kitasatospora aureofaciens
pyruvate + NH3 + NADH
-
-
-
?
1.4.1.1
L-Ala + H2O + nicotinamide guanine dinucleotide
59.9% of the activity with NAD+
349546
Kitasatospora aureofaciens
?
-
-
-
?