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Literature summary extracted from

  • Brox, L.W.; Hampton, A.
    Inosine 5-phosphate dehydrogenase. Kinetic mechanism and evidence for selective reaction of the 6-chloro analog of inosine 5-phosphate with a cysteine residue at the inosine 5-phosphate site (1968), Biochemistry, 7, 2589-2596.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.205 6-Chloro-9-beta-D-ribofuranosylpurine 5 '-phosphate 50% inactivation after 90 min at 0.00012 mM Cl-IMP Klebsiella aerogenes
1.1.1.205 6-Chloropurine ribonucleoside 5'-phosphate
-
 Klebsiella aerogenes
1.1.1.205 additional information
-
 Klebsiella aerogenes
1.1.1.205 NADH non competitive Klebsiella aerogenes
1.1.1.205 xanthosine 5'-phosphate non-competitive with respect to NAD Klebsiella aerogenes

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.205 200000
-
 sedimentation coefficient Klebsiella aerogenes

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.205 Klebsiella aerogenes
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.205
-
 Klebsiella aerogenes

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O
-
 Klebsiella aerogenes xanthosine 5'-phosphate + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.205 NAD+
-
 Klebsiella aerogenes