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Literature summary extracted from

  • Wermuth, B.
    NADP-dependent 15-hydroxyprostaglandin dehydrogenase is homologous to NAD-dependent 15-hydroxyprostaglandin dehydrogenase and other short-chain alcohol dehydrogenases (1992), Prostaglandins, 44, 5-9.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.197 beta-mercaptoacetate
-
 Homo sapiens
1.1.1.197 beta-mercaptolactate
-
 Homo sapiens
1.1.1.197 beta-Mercaptopyruvate
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.197 Homo sapiens
-
 human
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.197
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.197 brain
-
 Homo sapiens
-
1.1.1.197 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.197 prostaglandin B1 + NADP+
-
 Homo sapiens 15-oxoprostaglandin B1 + NADPH + H+
-
 ?
1.1.1.197 prostaglandin I2 + NADP+ poor substrate for the enzyme Homo sapiens ? + NADPH
-
 ?
1.1.1.197 thromboxane B2 + NADP+ slowly oxidized Homo sapiens ? + NADPH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.197 NADP+
-
 Homo sapiens