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Literature summary extracted from

  • Bohren, K.M.; Wermuth, B.; Harrison, D.; Ringe, D.; Petsko, G.A.; Gabbay, K.H.
    Expression, crystallization and preliminary crystallographic analysis of human carbonyl reductase (1994), J. Mol. Biol., 244, 659-664.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.184
-
 Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.184 recombinant protein from Escherichia coli Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.184 0.03
-
 menadione
-
 Homo sapiens
1.1.1.184 0.05
-
 5alpha-androstan-17beta-ol-3-one form CR2 Homo sapiens
1.1.1.184 0.1
-
 prostaglandin E2
-
 Homo sapiens
1.1.1.184 0.1
-
 5alpha-androstan-17beta-ol-3-one
-
 Homo sapiens
1.1.1.184 0.3
-
 daunorubicin
-
 Homo sapiens
1.1.1.184 0.3
-
 benzoylpyridine
-
 Homo sapiens
1.1.1.184 0.8
-
 2-nitrobenzaldehyde
-
 Homo sapiens
1.1.1.184 1
-
 Phenylglyoxal
-
 Homo sapiens
1.1.1.184 1.1
-
 4-nitrobenzaldehyde
-
 Homo sapiens
1.1.1.184 1.4
-
 pyridine-4-carboxaldehyde
-
 Homo sapiens
1.1.1.184 1.8
-
 2,3-Butanedione
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.184 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.184 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.184 2,3-butanedione + NADPH
-
 Homo sapiens ?
-
 ?
1.1.1.184 2-nitrobenzaldehyde + NADPH
-
 Homo sapiens 2-nitrobenzyl alcohol + NADP+
-
 ?
1.1.1.184 4-benzoylpyridine + NADPH
-
 Homo sapiens ?
-
 ?
1.1.1.184 4-nitrobenzaldehyde + NADPH
-
 Homo sapiens 4-nitrobenzyl alcohol + NADP+
-
 ?
1.1.1.184 5alpha-androstan-17beta-ol-3-one + NADPH
-
 Homo sapiens ?
-
 ?
1.1.1.184 benzoylpyridine + NADPH + H+
-
 Homo sapiens ?
-
 r
1.1.1.184 daunorubicin + NADPH
-
 Homo sapiens ?
-
 ?
1.1.1.184 menadione + NADPH
-
 Homo sapiens ?
-
 ?
1.1.1.184 phenylglyoxal + NADPH
-
 Homo sapiens ?
-
 ?
1.1.1.184 prostaglandin E2 + NADPH
-
 Homo sapiens ?
-
 ?
1.1.1.184 pyridine-4-carboxaldehyde + NADPH
-
 Homo sapiens ?
-
 ?