Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Martel, A.; Bouthier de la Tour, C.; le Goffic, F.
    Pyridoxal 5 phosphate binding site of Escherichia coli beta cystathionase and cystathionine gamma synthase comparison of their sequences (1987), Biochem. Biophys. Res. Commun., 147, 565-571.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.48 O-succinyl-L-homoserine + L-cysteine Salmonella enterica subsp. enterica serovar Typhimurium
-
 L-cystathionine + succinate
-
 ?
2.5.1.48 O-succinyl-L-homoserine + L-cysteine Escherichia coli key intermediate in transsulfuration pathways L-cystathionine + succinate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.48 Escherichia coli
-
-
-
2.5.1.48 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
4.4.1.13 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.48 O-succinyl-L-homoserine + L-cysteine
-
 Salmonella enterica subsp. enterica serovar Typhimurium L-cystathionine + succinate
-
 ?
2.5.1.48 O-succinyl-L-homoserine + L-cysteine key intermediate in transsulfuration pathways Escherichia coli L-cystathionine + succinate
-
 ?
4.4.1.13 L-cystathionine + H2O
-
 Escherichia coli L-homocysteine + NH3 + pyruvate
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.5.1.48 pyridoxal 5'-phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.5.1.48 pyridoxal 5'-phosphate binding site Escherichia coli
4.4.1.13 pyridoxal 5'-phosphate the pyridoxal 5'-phosphate binding site shows the tripeptide sequence Thr-Lys(Pxy)-Tyr in their structure Escherichia coli