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Literature summary extracted from

  • Gabius, H.J.; Freist, W.; Cramer, F.
    Phenylalanyl-tRNA synthetases from hen liver cytoplasm and mitochondria, yeast cytoplasm and mitochondria, and from Escherichia coli: substrate specificity relationship with regard to ATP analogs (1982), Hoppe-Seyler's Z. Physiol. Chem., 363, 1241-1246.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.20 2',3'-Ribodeoxy-ATP
-
 Gallus gallus
6.1.1.20 2',3'-Ribodeoxy-ATP
-
 Saccharomyces cerevisiae
6.1.1.20 3'-Deoxyadenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.20 3'-Deoxyadenosine 5'-triphosphate
-
 Gallus gallus
6.1.1.20 3'-Deoxyadenosine 5'-triphosphate
-
 Saccharomyces cerevisiae
6.1.1.20 3'-Methyladenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.20 3'-Methyladenosine 5'-triphosphate
-
 Gallus gallus
6.1.1.20 N6-Benzyladenosine 5'-triphosphate
-
 Gallus gallus
6.1.1.20 N6-Benzyladenosine 5'-triphosphate
-
 Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.1.1.20 0.008
-
 ATP cytoplasmic Saccharomyces cerevisiae
6.1.1.20 0.009
-
 ATP
-
 Escherichia coli
6.1.1.20 0.055
-
 ATP mitochondrial Saccharomyces cerevisiae
6.1.1.20 0.065
-
 ATP mitochondrial Gallus gallus
6.1.1.20 0.085
-
 2'-deoxyadenosine 5'-triphosphate mitochondrial Saccharomyces cerevisiae
6.1.1.20 0.096
-
 2-Chloroadenosine 5'-triphosphate mitochondrial Gallus gallus
6.1.1.20 0.11
-
 2-Chloroadenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.20 0.125
-
 2'-deoxyadenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.20 0.14
-
 ATP cytoplasmic Gallus gallus
6.1.1.20 0.16
-
 2-Chloroadenosine 5'-triphosphate cytoplasmic Gallus gallus
6.1.1.20 0.16
-
 2-Chloroadenosine 5'-triphosphate mitochondrial Saccharomyces cerevisiae
6.1.1.20 0.19
-
 2'-deoxyadenosine 5'-triphosphate cytoplasmic Gallus gallus
6.1.1.20 0.2
-
 2-Chloroadenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.20 0.2
-
 2-Chloroadenosine 5'-triphosphate mitochondrial, 3'-deoxyadenosine 5'-triphosphate Saccharomyces cerevisiae
6.1.1.20 0.2
-
 2-Chloroadenosine 5'-triphosphate cytoplasmic, 2'-deoxyadenosine 5'-triphosphate Saccharomyces cerevisiae
6.1.1.20 0.3
-
 3'-deoxadenosine 5'-triphosphate cytoplasmic Gallus gallus
6.1.1.20 0.4
-
 2'-deoxyadenosine 5'-triphosphate cytoplasmic Gallus gallus
6.1.1.20 1
-
 3'-Deoxyadenosine 5'-triphosphate mitochondrial Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.1.1.20 cytoplasm
-
 Gallus gallus 5737
-
6.1.1.20 cytoplasm
-
 Saccharomyces cerevisiae 5737
-
6.1.1.20 mitochondrion
-
 Gallus gallus 5739
-
6.1.1.20 mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.20 Escherichia coli
-
-
-
6.1.1.20 Gallus gallus
-
-
-
6.1.1.20 Saccharomyces cerevisiae
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.1.1.20 liver
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.20 2'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
 Gallus gallus 2'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 2'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
 Escherichia coli 2'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 2'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
 Saccharomyces cerevisiae 2'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 2-chloroadenosine 5'-triphosphate + phenylalanine + tRNAPhe
-
 Gallus gallus 2-chloroadenosine 5'-monophosphate + diphosphate + phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 2-chloroadenosine 5'-triphosphate + phenylalanine + tRNAPhe
-
 Escherichia coli 2-chloroadenosine 5'-monophosphate + diphosphate + phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 2-chloroadenosine 5'-triphosphate + phenylalanine + tRNAPhe
-
 Saccharomyces cerevisiae 2-chloroadenosine 5'-monophosphate + diphosphate + phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 3'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
 Gallus gallus 3'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 3'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
 Escherichia coli 3'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 3'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
 Saccharomyces cerevisiae 3'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 ATP + L-phenylalanine + tRNAPhe
-
 Gallus gallus AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 ATP + L-phenylalanine + tRNAPhe
-
 Escherichia coli AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
6.1.1.20 ATP + L-phenylalanine + tRNAPhe
-
 Saccharomyces cerevisiae AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?