EC Number | Application | Comment | Organism |
---|---|---|---|
4.2.1.9 | analysis | the enzyme is used to quantify and investigate the biological oxidant stress activity of various redox-cycling chemicals. High sensitivity to inactivation by oxidants makes the enzyme useful for identification of compounds which increase oxyradical flux in the cell and for probing their mechanism of action | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.9 | 3-(5-nitrofuran-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole hydrochloride | - |
Escherichia coli | |
4.2.1.9 | benzoquinone | - |
Escherichia coli | |
4.2.1.9 | duroquinone | - |
Escherichia coli | |
4.2.1.9 | hydralazine | - |
Escherichia coli | |
4.2.1.9 | juglone | - |
Escherichia coli | |
4.2.1.9 | Nitrofurantoin | - |
Escherichia coli | |
4.2.1.9 | paraquat | - |
Escherichia coli | |
4.2.1.9 | Plumbagin | - |
Escherichia coli |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.9 | Iron | contains a catalytically active [4Fe-4S] cluster | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.9 | Escherichia coli | - |
K-12 | - |
4.2.1.9 | Escherichia coli | - |
CGSC strain 5073 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.9 | 2,3-dihydroxy-3-methylbutanoate | - |
Escherichia coli | 2-oxoisovalerate + H2O | - |
? | |
4.2.1.9 | 2,3-dihydroxy-3-methylpentanoate | - |
Escherichia coli | 3-methyl-2-oxopentanoate + H2O | - |
? |