Literature summary extracted from

Flint, D.H.; Smyk-Randall, E.; Tuminello, J.F.; Draczynska-Lusiak, B.; Brown, O.R.
The inactivation of dihydroxy-acid dehydratase in Escherichia coli treated with hyperbaric oxygen occurs because of the destruction of its Fe-S cluster, but the enzyme remains in the cell in a form that can be reactivated (1993), J. Biol. Chem., 268, 25547-25552.

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.1.9	Escherichia coli	-	-	-

Oxidation Stability

EC Number	Oxidation Stability	Organism
4.2.1.9	inactivation by exposure to hyperbaric O2 is due to the destruction of its catalytically active 4Fe-4S cluster. Reactivation occurs by reconstitution of the enzyme's Fe-S cluster	Escherichia coli

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.1.9	2,3-dihydroxy-3-methylbutanoate	-	Escherichia coli	2-oxoisovalerate + H2O	-	?
4.2.1.9	2,3-dihydroxy-3-methylpentanoate	-	Escherichia coli	3-methyl-2-oxopentanoate + H2O	-	?

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Release 2023.1 (January 2023)