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Literature summary extracted from

  • Zhu, X.L.; Sly, W.S.
    Carbonic anhydrase IV from human lung. Purification, characterization, and comparison with membrane carbonic anhydrase from human kidney (1990), J. Biol. Chem., 265, 8795-8801.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.1 acetazolamide
-
 Homo sapiens
4.2.1.1 Cl- relatively resistant to Homo sapiens
4.2.1.1 I- relatively resistant to Homo sapiens
4.2.1.1 sulfanilamide
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.2.1.1 membrane at least half of the carbonic anhydrase IV in lung and kidney is anchored to membranes by phosphatidylinositol-glycan linkages Homo sapiens 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.1 35000
-
 x * 35000, calculation from amino acid composition Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.1 Homo sapiens
-
 carbonic anhydrase IV
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
4.2.1.1 additional information contains no N-linked or O-linked oligosaccharides Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.1
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.1 kidney carbonic anhydrase IV Homo sapiens
-
4.2.1.1 lung carbonic anhydrase IV Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
4.2.1.1 4°C, stable for at least 1 year Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.1 CO2 + H2O
-
 Homo sapiens H2CO3
-
 ?

Subunits

EC Number Subunits Comment Organism
4.2.1.1 ? x * 35000, calculation from amino acid composition Homo sapiens