Any feedback?
Literature summary extracted from
- The specificity of macrophage elastase on the insulin B-chain (1981), Biochem. J., 195, 369-372.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.65 | EDTA | - |
Mus musculus |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.24.65 | extracellular | - |
Mus musculus | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.65 | Mus musculus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.24.65 | - |
Mus musculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.24.65 | macrophage | serum-free culture medium conditioned by thioglycollate-elicited peritoneal exudative macrophages | Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.65 | Insulin B-chain + H2O | hydrolyzes Ala-Leu and Tyr-Leu, not His10-Leu11, on amino side of Leu-residue, not Val-residue | Mus musculus | ? | - |
? | |
| 3.4.24.65 | additional information | no substrates are Glu-Ala-Leu-Tyr-Leu-Val (i.e. residues 13-18 of insulin B-chain) | Mus musculus | ? | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.65 | 37 | - |
assay at | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
