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Literature summary extracted from

  • Rao, N.V.; Wehner, N.G.; Marshall, B.C.; Gray, W.R.; Gray, B.H.; Hoidal, J.R.
    Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties (1991), J. Biol. Chem., 266, 9540-9548.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.76 Alpha1-proteinase inhibitor
-
Homo sapiens
3.4.21.76 alpha2-Macroglobulin
-
Homo sapiens
3.4.21.76 Eglin c weak Homo sapiens
3.4.21.76 additional information not: alpha1-anti-chymotrypsin; secretory leukocyte proteinase inhibitor Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.76 azurophil granule from human polymorphonuclear leukocytes (PMNL) Homo sapiens 42582
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.76 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.76 polymorphonuclear leukocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.76 Collagen type IV + H2O no or minimal activity against interstitial collagens type I and III Homo sapiens Hydrolyzed collagen type IV
-
?
3.4.21.76 Fibronectin + H2O
-
Homo sapiens Hydrolyzed fibronectin
-
?
3.4.21.76 laminin + H2O
-
Homo sapiens fragments of laminin
-
?
3.4.21.76 Vitronectin + H2O
-
Homo sapiens Hydrolyzed vitronectin
-
?