EC Number | Application | Comment | Organism |
---|---|---|---|
3.7.1.3 | medicine | tryptophan metabolism | Homo sapiens |
3.7.1.3 | medicine | tryptophan metabolism | Rattus norvegicus |
3.7.1.3 | medicine | tryptophan metabolism | Suncus murinus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.7.1.3 | 0.013 | - |
L-3-hydroxykynurenine | - |
Rattus norvegicus | |
3.7.1.3 | 0.018 | - |
L-3-hydroxykynurenine | - |
Suncus murinus | |
3.7.1.3 | 0.077 | - |
L-3-hydroxykynurenine | - |
Homo sapiens | |
3.7.1.3 | 0.24 | - |
L-kynurenine | - |
Rattus norvegicus | |
3.7.1.3 | 0.25 | - |
L-kynurenine | - |
Suncus murinus | |
3.7.1.3 | 1 | - |
L-kynurenine | - |
Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.7.1.3 | 95000 | - |
- |
Rattus norvegicus |
3.7.1.3 | 110000 | - |
- |
Suncus murinus |
3.7.1.3 | 130000 | - |
- |
Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | Homo sapiens | - |
3-hydroxyanthranilate + L-Ala | - |
? | |
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | Rattus norvegicus | - |
3-hydroxyanthranilate + L-Ala | - |
? | |
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | Suncus murinus | - |
3-hydroxyanthranilate + L-Ala | - |
? | |
3.7.1.3 | L-kynurenine + H2O | Homo sapiens | - |
anthranilate + L-alanine | - |
? | |
3.7.1.3 | L-kynurenine + H2O | Rattus norvegicus | - |
anthranilate + L-alanine | - |
? | |
3.7.1.3 | L-kynurenine + H2O | Suncus murinus | - |
anthranilate + L-alanine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.7.1.3 | Homo sapiens | - |
- |
- |
3.7.1.3 | Rattus norvegicus | - |
- |
- |
3.7.1.3 | Suncus murinus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.7.1.3 | adrenal gland | - |
Homo sapiens | - |
3.7.1.3 | adrenal gland | - |
Rattus norvegicus | - |
3.7.1.3 | adrenal gland | - |
Suncus murinus | - |
3.7.1.3 | brain | - |
Homo sapiens | - |
3.7.1.3 | brain | - |
Rattus norvegicus | - |
3.7.1.3 | brain | - |
Suncus murinus | - |
3.7.1.3 | heart | - |
Homo sapiens | - |
3.7.1.3 | heart | - |
Rattus norvegicus | - |
3.7.1.3 | heart | - |
Suncus murinus | - |
3.7.1.3 | intestinal muscle | - |
Homo sapiens | - |
3.7.1.3 | intestinal muscle | - |
Rattus norvegicus | - |
3.7.1.3 | intestinal muscle | - |
Suncus murinus | - |
3.7.1.3 | kidney | - |
Homo sapiens | - |
3.7.1.3 | kidney | - |
Rattus norvegicus | - |
3.7.1.3 | kidney | - |
Suncus murinus | - |
3.7.1.3 | liver | - |
Homo sapiens | - |
3.7.1.3 | liver | - |
Rattus norvegicus | - |
3.7.1.3 | liver | - |
Suncus murinus | - |
3.7.1.3 | lung | - |
Homo sapiens | - |
3.7.1.3 | lung | - |
Rattus norvegicus | - |
3.7.1.3 | lung | - |
Suncus murinus | - |
3.7.1.3 | muscle | - |
Rattus norvegicus | - |
3.7.1.3 | muscle | - |
Suncus murinus | - |
3.7.1.3 | ovary | - |
Homo sapiens | - |
3.7.1.3 | pancreas | - |
Homo sapiens | - |
3.7.1.3 | pancreas | - |
Rattus norvegicus | - |
3.7.1.3 | pancreas | - |
Suncus murinus | - |
3.7.1.3 | spleen | - |
Homo sapiens | - |
3.7.1.3 | spleen | - |
Rattus norvegicus | - |
3.7.1.3 | spleen | - |
Suncus murinus | - |
3.7.1.3 | thymus | - |
Suncus murinus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.7.1.3 | 0.0002 | - |
liver | Rattus norvegicus |
3.7.1.3 | 0.0007 | - |
liver | Homo sapiens |
3.7.1.3 | 0.026 | - |
liver | Suncus murinus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | - |
Homo sapiens | 3-hydroxyanthranilate + L-alanine | - |
? | |
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | - |
Rattus norvegicus | 3-hydroxyanthranilate + L-alanine | - |
? | |
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | - |
Suncus murinus | 3-hydroxyanthranilate + L-alanine | - |
? | |
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | - |
Homo sapiens | 3-hydroxyanthranilate + L-Ala | - |
? | |
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | - |
Rattus norvegicus | 3-hydroxyanthranilate + L-Ala | - |
? | |
3.7.1.3 | 3-hydroxy-L-kynurenine + H2O | - |
Suncus murinus | 3-hydroxyanthranilate + L-Ala | - |
? | |
3.7.1.3 | L-kynurenine + H2O | - |
Homo sapiens | anthranilate + L-alanine | - |
? | |
3.7.1.3 | L-kynurenine + H2O | - |
Rattus norvegicus | anthranilate + L-alanine | - |
? | |
3.7.1.3 | L-kynurenine + H2O | - |
Suncus murinus | anthranilate + L-alanine | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.7.1.3 | dimer | - |
Rattus norvegicus |
3.7.1.3 | dimer | - |
Suncus murinus |