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Literature summary extracted from

  • Kvittingen, E.A.; Rootwelt, H.; Brandtzaeg, P.; Bergan, A.; Berger, R.
    Hereditary tyrosinemia type I (1993), J. Clin. Invest., 91, 1816-1821.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
3.7.1.2 medicine plays a role in hereditary tyrosinemia Homo sapiens
3.7.1.2 medicine plays a role in degradation pathway of phenylalanine and tyrosine Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.7.1.2 0.8 1.2 Fumarylacetoacetate liver, dependent on patients Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.7.1.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.7.1.2 fibroblast
-
 Homo sapiens
-
3.7.1.2 liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.7.1.2 0.0004 0.032 liver, dependent on patients Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.7.1.2 4-fumarylacetoacetate + H2O
-
 Homo sapiens acetoacetate + fumarate
-
 ?