Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Morikawa, K.; Matsumoto, O.; Tsujimoto, M.; Katayanagi, K.; Ariyoshi, M.; Doi, T.; Ikehara, M.; Inaoka, T.; Ohtsuka, E.
    X-ray structure of T4 endonuclease V: An excision repair enzyme specific for a pyrimidine dimer (1992), Science, 256, 523-526.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.1.21.7 2.5 A resolution Tequatrovirus T4

Protein Variants

EC Number Protein Variants Comment Organism
3.1.21.7 E23Q retains ability to bind the substrate Tequatrovirus T4
3.1.21.7 R3Q greatly decreased DNA binding ability Tequatrovirus T4

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.21.7 DNA + H2O Tequatrovirus T4 pyrimidine dimer-specific 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?
3.1.21.7 DNA + H2O Tequatrovirus T4 two distinct activities: pyrimidine dimer glycosylase and apurinic-apyrimidinic endonuclease, beta-elimination of the 3'-phosphate of an abasic site 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?
3.1.21.7 double-stranded plasmid DNA + H2O Tequatrovirus T4
-
 nicked circular DNA + linearized DNA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.21.7 Tequatrovirus T4
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.21.7 DNA + H2O pyrimidine dimer-specific Tequatrovirus T4 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?
3.1.21.7 DNA + H2O two distinct activities: pyrimidine dimer glycosylase and apurinic-apyrimidinic endonuclease, beta-elimination of the 3'-phosphate of an abasic site Tequatrovirus T4 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?
3.1.21.7 double-stranded plasmid DNA + H2O
-
 Tequatrovirus T4 nicked circular DNA + linearized DNA
-
 ?