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Literature summary extracted from
- Isolation and properties of glycerol-3-phosphate oxidoreductase from human placenta (1986), Eur. J. Biochem., 154, 161-166.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 1.1.1.8 | ammonium sulfate inactivates | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.8 | (NH4)2SO4 | - |
Homo sapiens |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.8 | 0.005 | - |
NADH | measured at pH 7.5 | Homo sapiens | |
| 1.1.1.8 | 0.026 | - |
dihydroxyacetone phosphate | measured at pH 7.5 | Homo sapiens | |
| 1.1.1.8 | 0.036 | - |
NAD+ | measured at pH 9.0 | Homo sapiens | |
| 1.1.1.8 | 0.143 | - |
sn-glycerol-3-phosphate | measured at pH 9.0 | Homo sapiens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.8 | 38000 | - |
2 * 38000, SDS-PAGE | Homo sapiens |
| 1.1.1.8 | 62000 | - |
gel filtration | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.8 | sn-glycerol 3-phosphate + NAD+ | Homo sapiens | - |
dihydroxyacetone phosphate + NADH + H+ | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.8 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.8 | affinity chromatography | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.8 | placenta | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.8 | 88.2 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.8 | sn-glycerol 3-phosphate + NAD+ | - |
Homo sapiens | dihydroxyacetone phosphate + NADH + H+ | - |
r | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.1.8 | dimer | 2 * 38000, SDS-PAGE | Homo sapiens |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.8 | 6.7 | 8.7 | about 80% of maximal activity at pH 6.7 and 8.7, reduction of dihydroxyacetone phosphate, decrease of activity below and above these pH values | Homo sapiens |
| 1.1.1.8 | 8.1 | 9.4 | about 80% of maximal activity at pH 8.1 and 9.4, oxidation of glycerol-3-phosphate, decrease of activity below and rapidly above these pH values | Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.8 | NAD+ | - |
Homo sapiens | |
| 1.1.1.8 | NADH | - |
Homo sapiens | |
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