EC Number | General Stability | Organism |
---|---|---|
1.1.1.8 | NADH stabilizes | Drosophila melanogaster |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.8 | ATP | - |
Drosophila melanogaster |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.8 | additional information | - |
additional information | Km values of isozyme GPDH-3 | Drosophila melanogaster | |
1.1.1.8 | 0.078 | - |
NADH | GPDH-1 | Drosophila melanogaster | |
1.1.1.8 | 0.38 | - |
NAD+ | GPDH-1 | Drosophila melanogaster | |
1.1.1.8 | 0.52 | - |
dihydroxyacetone phosphate | GPDH-1 | Drosophila melanogaster | |
1.1.1.8 | 0.59 | - |
glycerol 3-phosphate | GPDH-1 | Drosophila melanogaster |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.8 | sn-glycerol 3-phosphate + NAD+ | Drosophila melanogaster | - |
dihydroxyacetone phosphate + NADH + H+ | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.8 | Drosophila melanogaster | - |
fruit fly, Samarkand wild-type | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.8 | 3 isozymes, product of the same gene mapped to left arm of chromosome II, isozyme 1: flight muscle, isozyme 3: larval and adult fat body, isozyme 2: heterodimer of 1 and 3 | Drosophila melanogaster |
1.1.1.8 | affinity chromatography | Drosophila melanogaster |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.8 | muscle | thoracic flight muscle | Drosophila melanogaster | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.1.1.8 | 156 | - |
isozyme GPDH-3 | Drosophila melanogaster |
1.1.1.8 | 179.8 | - |
isozyme GPDH-1 | Drosophila melanogaster |
EC Number | Storage Stability | Organism |
---|---|---|
1.1.1.8 | 5°C, isozyme 1: stable for over a month in 10 mM sodium phosphate buffer, pH 6.5, with added EDTA, dithiothreitol and NADH, isozyme 3: 50% loss of activity under the same conditions | Drosophila melanogaster |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.8 | sn-glycerol 3-phosphate + NAD+ | - |
Drosophila melanogaster | dihydroxyacetone phosphate + NADH + H+ | - |
r |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.1.1.8 | 6.8 | - |
reduction of dihydroxyacetone-P, isozyme GPDH-1 | Drosophila melanogaster |
1.1.1.8 | 7.4 | - |
reduction of dihydroxyacetone-phosphate, isozyme GPDH-3 | Drosophila melanogaster |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.8 | NAD+ | - |
Drosophila melanogaster | |
1.1.1.8 | NADH | - |
Drosophila melanogaster |